IMPACT OF TOBACCO USE IN PREGNANT WOMEN ON FETAL GROWTH AND SHORT- AND LONG-TERM NEONATAL DEVELOPMENT

Authors

Keywords:

Pregnancy; Newborn; Maternal health; Smoking

Abstract

DOI: https://doi.org/10.46296/gt.v9i18edespsep.0423

Abstract

Tobacco use during pregnancy is a public health issue due to its association with adverse maternal, fetal, and neonatal outcomes. The objective was to analyze the impact of tobacco use in pregnant women and its primary consequences for maternal, fetal, and newborn health. A systematic review was conducted following the PRISMA 2021 statement. PubMed, SciELO, ScienceDirect, and Redalyc were searched for publications from 2021 to 2026. Original articles and reviews directly related to smoking during pregnancy and its maternal, fetal, or perinatal effects—published in either Spanish or English—were included. Information was organized using the structuring method and an evidence synthesis matrix. The reviewed evidence showed consistent associations between maternal smoking and low birth weight, preterm birth, fetal growth restriction, and increased admission to neonatal intensive care units. Potential effects on infant cognitive and motor development were identified, as well as associations with certain urogenital malformations. However, not all outcomes showed significant associations; this was the case for autism spectrum disorder.

Keywords: Pregnancy; Newborn; Maternal health; Smoking.

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References

Alhage, M., Arutkin, M., Ceccaldi, P., Josseran, L., Ayoubi, J., & Vallée, A. (2026). Management of tobacco smoking among pregnant women: A qualitative study with French midwives to inform local practice recommendations. Womens Health. doi:https://doi.org/10.1177/17455057261427550

Ambildhok, K., & Asawa, K. (2026). The Consequences of Prenatal Tobacco Exposure: A Systematic Review of Birth Outcomes and Developmental Trajectories. Cureus, 18(3), e105888. doi:https://doi.org/10.7759/cureus.105888

Banegas, H. (2022). CONOCIMIENTO SOBRE LACTANCIA MATERNA EXCLUSIVA EN MADRES ADOLESCENTES DEL SERVICIO DE GINECO – OBSTETRICIA DEL HOSPITAL REGIONAL MANUEL NÚÑEZ BUTRÓN PUNO 2019. evista De Investigación Científica En Ciencias De La Salud,, 9. Obtenido de http://csalud.unat.edu.pe/index.php/RDE/article/view/17

Calderón, K. D. (2025). Tabaquismo materno relacionado con el ingreso a unidades de cuidados intensivos neonatales: una revisión sistemática. Journal Nursing Valencia(5). Obtenido de https://www.journursval.com/index.php/jnv/article/view/31

Castro Borja, V. M. (2019). Efecto de un programa educativo sobre el conocimiento de lactancia materna exclusiva en madres adolescentes en un Puesto de Salud de Lima, 2019. UPLA, 25. Obtenido de https://repositorio.upla.edu.pe/handle/20.500.12848/1840

Cevik, J., Salehi, O., Gaston, J., & Rozen, W. (2023). Maternal Cigarette Smoking and Congenital Upper and Lower Limb Differences: A Systematic Review and Meta-Analysis. J Clin Med., 12(13). doi:https://doi.org/10.3390/jcm12134181

Davia-Cantos, M. J., Tárraga-Marcos, L., Tárraga-Marcos, A., & Tárraga-López, P. J. (2022). Patología orgánica asociada al tabaquismo. Journal of Negative and No Positive Results, 7(4), 385-408. doi:https://dx.doi.org/10.19230/jonnpr.4801

Duko, B., Pereira, G., Tait, R., Nyadanu, S., Betts, K., & Alati, R. (2021). Prenatal Tobacco Exposure and the Risk of Tobacco Smoking and Dependence in Offspring: a Systematic Review and Meta-Analysis. Drug Alcohol Depend. doi:https://doi.org/10.1016/j.drugalcdep.2021.108993

Fonseca, J. M., Silva, A. A., Rocha, P. R., Batista, R. L., Thomaz, E. B., Lamy-Filho, F., . . . Bettiol, H. (2021). Racial inequality in perinatal outcomes in two Brazilian birth cohorts. Brazilian Journal of Medical and Biological Research, 54(1), e10120. doi:https://doi.org/10.1590/1414-431X202010120

García, R. C. (2025). Abordaje del tabaquismo pasivo en el embarazo y la infancia. FMC-Formación Médica Continuada en Atención Primaria, 32(2), 58-63. doi:https://doi.org/10.1016/j.fmc.2024.06.001

Liu, W., Yu, W., Zhang, K., & Wang, M. (2026). Associations between maternal smoking around birth and hepatocellular carcinoma: A bidirectional two-sample Mendelian randomization study in East Asian populations. Tob Induc Dis. doi:https://doi.org/10.18332/tid/218848

Nastacuas, A. C., Ponluisa, A. J., & Andrade, C. R. (2026). Impacto del consumo del tabaco durante el embarazo. Reincisol, 5(9), 1446-1446. doi:https://doi.org/10.59282/reincisol.V5(9)1446

OMS. (2025 ). Effects of tobacco on health. Organizacion Mundial de la Salud. Obtenido de https://www.who.int/europe/news-room/fact-sheets/item/effects-of-tobacco-on-health

OMS. (2026). Tabaco y nicotina. Organizacion Mundial de la Salud. Obtenido de https://www.who.int/es/news-room/fact-sheets/detail/tobacco

Pavesi, E., Amorim, M. V., Boing, A. F., & Wagner, K. J. (2023). Influence of alcohol and tobacco consumption on maternal and perinatal outcomes of puerperal women attended at the Brazilian National Health System. Revista Brasileira De Saúde Materno Infantil(23), e20220286. doi:https://doi.org/10.1590/1806-9304202300000286-en

Peltekidi, A., Jotautis, V. T.-C., Georgakopoulou, V., Sousamli, A., Diamanti, A., Vivilaki, V., . . . Sarantaki, A. (2025). Maternal Smoking During Pregnancy and Risk of Autism Spectrum Disorder in Offspring: A Systematic Review and Meta-Analysis. J Clin Med., 14(23), 8584. doi:https://doi.org/10.3390/jcm14238584

Rocha, P. R., Silva, G. P., Gratão, O. A., Barbieri, M. A., Cardoso, V. C., Saraiva, M. d., & Bettiol, H. (2025). Factors associated with developmental delay in late preterm infants: the BRISA cohort. Jornal De Pediatria, 101(4), 657–664. doi:https://doi.org/10.1016/j.jped.2025.04.002

UNICEF. (14 de 07 de 2023). UNICEF. Obtenido de El impacto del COVID-19 en la salud mental de adolescentes y jóvenes: https://www.unicef.org/lac/el-impacto-del-covid-19-en-la-salud-mental-de-adolescentes-y-j%C3%B3venes

Weller, E., Aarsman, S., Teague, S., Greenwood, C., Youssef, G., Mattick, R., . . . Hutchinson, D. (2026). Perinatal smoking in mothers and fathers: Longitudinal associations with infant birth outcomes in the Triple B Pregnancy Cohort Study. Drug Alcohol Depend(286), 113262. doi:10.1016/j.drugalcdep.2026.113262.

Zhang, Q., Zhang, Z., He, X., Liu, Z., Wei, G., & Liu, X. (2022). Maternal smoking during pregnancy and the risk of congenital urogenital malformations: A systematic review and meta-analysis. Front Pediatr. doi:https://doi.org/10.3389/fped.2022.973016

Published

2026-09-11

How to Cite

Llango-Caiza, W. F., Changoluisa-Guachamboza, R. E., & Velasco-Acurio, E. F. (2026). IMPACT OF TOBACCO USE IN PREGNANT WOMEN ON FETAL GROWTH AND SHORT- AND LONG-TERM NEONATAL DEVELOPMENT. GESTAR Arbitrated Scientific Journal in Health Research. ISSN: 2737-6273., 9(18 Ed. Esp.), 450-468. Retrieved from https://journalgestar.org/index.php/gestar/article/view/428